Alzheimer's Drug Helps Mice

Level 2 Source: vice.com

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A brown mouse sitting in the gloved hand of a researcher.
Scientists were able to help mice.

Scientists say they brought back brain function in mice with Alzheimer's disease. Alzheimer's is a brain disease. It slowly takes away a person's memory and thinking. It mostly affects people over 65. It is the main cause of dementia (when the brain stops working well). More than 150 million people could have dementia by 2050.

The scientists tested a new drug on sick mice. The drug helped the mice's brains get energy again. Even very sick mice got better after the treatment. Their brains started working normally again.

The scientists tested the drug on two different groups of mice. In both groups, the drug stopped the disease or brought back brain function. The scientists now think that even very bad Alzheimer's can get better.

But the drug is not ready for people. Scientists still have to test it on humans. This is going to take many years. But for the first time, scientists believe they can do more than just slow Alzheimer's. They think they can bring back what the disease takes away.

Speaker: American Male  Duration: 1:28  Watch on YouTube

Two ways to use this audio:

  • Method 1: Listen for the main idea: what is the article about in one sentence? Listen a second time for more details, then try the Understanding activities below.
  • Method 2: Read the article first to learn the vocabulary and ideas. Then look at the gap-fill sentences to see what to listen for, and listen to fill them in.

Listen and Fill Gaps

Scientists say they brought back brain function in mice with Alzheimer's disease. Alzheimer's is a brain disease. It slowly takes away a person's (1) and thinking. It mostly affects people over 65. It is the main (2) of dementia (when the brain stops working well). More than 150 million people could have dementia by 2050.

The scientists tested a new drug on sick mice. The drug helped the mice's brains get (3) again. Even very sick mice got better after the treatment. Their brains started working normally again.

The scientists tested the drug on two different (4) of mice. In both groups, the drug stopped the disease or brought back brain function. The scientists now think that even very bad Alzheimer's can get better.

But the drug is not ready for people. Scientists still have to test it on humans. This is going to take many years. But for the first time, scientists believe they can do more than just (5) Alzheimer's. They think they can bring back what the disease takes away.

True or False

Answer each question by selecting True or False, then click CHECK to see your results.

  • Alzheimer's disease mostly affects people over 65.
    The article says it mostly affects people over 65.
  • The scientists tested the drug on humans.
    The article says the drug is not ready for people and scientists still have to test it on humans.
  • The drug is ready for people now.
    The article says the drug is not ready for people and testing on humans is going to take many years.

True or False

1. Alzheimer's disease mostly affects people over 65. TRUEFALSE True

2. The scientists tested the drug on humans. TRUEFALSE False

3. The drug is ready for people now. TRUEFALSE False

Put Events in Order

  • Scientists will test the drug on humans.
  • Scientists tested a new drug on sick mice.
  • In 2050, more than 150 million people could have dementia.
  • The drug helped the mice's brains get energy again.
  1. Scientists tested a new drug on sick mice.
  2. The drug helped the mice's brains get energy again.
  3. Scientists will test the drug on humans.
  4. In 2050, more than 150 million people could have dementia.

Multiple Choice

1. What did the new drug help the mice's brains do?

   a) Get energy againCorrect

   b) Grow bigger

   c) Make new cells

   d) Sleep better

2. How many people could have dementia by 2050?

   a) About 50 million

   b) About 100 million

   c) More than 150 millionCorrect

   d) More than 200 million

3. What do the scientists now believe they can do?

   a) Stop all brain diseases

   b) Help only young mice

   c) Slow Alzheimer's only

   d) Bring back what the disease takes awayCorrect

Vocab Match

Loading vocabulary activity...

Vocab Match

1. Diseasee) A sickness that affects the body or mind.

2. Memoryd) The ability to remember things.

3. Treatmentc) Something done to make a sick person better.

4. Functionb) The way something works.

5. Dementiaa) When the brain stops working well.

a) When the brain stops working well.

b) The way something works.

c) Something done to make a sick person better.

d) The ability to remember things.

e) A sickness that affects the body or mind.

Discussion Builder

Discussion Builder

  1. I think, / But, / So,

    More than 150 million people could have dementia by 2050. I think, that is a very big number.

  2. because / and / but

    Scientists need more time because the drug is not ready for people.

  3. For example, / But, / So,

    The drug worked on very sick mice. So, scientists are very happy about the results.

Discussion Questions

  1. How does this article make you feel? Why?
  2. What things do you remember well?
  3. What kinds of things do you often forget?
  4. Are you worried about getting old?
  5. Who is the oldest person you know? How are they different from you?
  6. What do you do to keep your brain healthy?
  7. Have you ever taken care of a sick person? What was it like?
  8. Why do you think scientists test drugs on mice first?
  9. What other diseases do you think need more research?